Antidepressants

What are Antidepressants?

Antidepressants are medicine for depressed people. Most people who take antidepressant medicine feel better after treatment.

How Antidepressants Work?

Antidepressants In antidepressants, some chemicals in brain are removed. These chemicals are also called as neurotransmitters. These are needed for brain function. Antidepressant treatment is given to patients for 4 to 6 months. In some cases it requires longer time.

Types of Antidepressants

Tricyclic Drug

Tricyclic drug was discovered in 1950 and still very much used to treat depression. It is also known as TCA. Tricyclic is the first treatment for major depression. In this treatment level of serotonin and norepinephrine is raised in the brain by showing the rate of reuptake, or reabsorption, by nerve cells. Tricyclic drug takes several weeks for better result. Some antidepressants side effect are also seen in some patients.

Commonly used Tricyclic antidepressant medicine is as follows

  • amitriptyline
  • desipramine
  • imipramine
  • nortriptyline

Side Effects of Tricyclic Drug Antidepressant Medicine

  • Dry mouth
  • Constipation
  • Bladder Problem
  • Sexual Problem
  • Blurried Vision
  • Dizziness
  • Drowsiness as a daytime problem
  • Increased Heart rate

Selective Serotonin Reuptake Inhibitors (SSRIs)

This is one of the major types of antidepressants medicine. SSRIs was found in 1980s and is most commonly in use. This medicine has fewer side effects than other antidepressants medicines. It is also less sedative than other medicine.

Imbalance of certain neurotransmitters is one of the main cause of depression. SSRis works by regulating the neurochemical serotonin. This type of antidepressant medicine uses the reduced amount of serotonin that it has at that time.

Commonly used SSRIs antidepressant medicine is as follows

  • citalopram
  • escitalopram
  • fluoxetine
  • paroxetine
  • sertraline

Side Effects of SSRIs Drug Antidepressant Medicine

  • Dry mouth
  • Nausea
  • Nervousness
  • Insomnia
  • Sexual problems
  • Headache

Monamine Oxidase Inhibitors (MAOIs)

This type of antidepressant medicine is less used than other medicines. These MAOIs suit to only small number of people. In Monamine oxidase inhibitors, there is restriction on food where as in other treatments, no restriction on food.

This medicine interacts with the other medicine. Interaction with other medicine can cause dangerous elevations in blood pressure or other potentially life-threatening reactions.

Commonly used Monamine oxidase inhibitors antidepressant medicine is as follows

  • Isocarboxazid
  • Phenelzine
  • Tranlcypromine

Side Effects of Monamine oxidase inhibitors Drug Antidepressant Medicine

  • Weakness
  • Dizziness
  • Headaches
  • Trembling

Norepinephrine and Dopamine Reuptake Inhibitors (NDRIs)

Commonly used Norepinephrine and dopamine reuptake inhibitors (NDRIs) is bupropion.

Side Effects of NDRIs Antidepressant Medicine

  • Agitation
  • Nausea
  • Headache
  • Loss of appetite
  • Insomnia

NDRIs also causes increase blood pressure in some people.

Combined Reuptake Inhibitors and Receptor Blockers

Commonly used combined reuptake inhibitors and receptor blockers medicine is as follows

  • Trazodone
  • Nefazodone
  • Maprotiline
  • Mirtazpine

Side Effects of Combined reuptake inhibitors and receptor blockers Medicine

  • Drowsiness
  • Dry mouth
  • Nause
  • Dizziness

Benefits from Antidepressants Medicine.

Antidepressants medicines removes almost 85% symptoms of depression. For example, it improves energy level, reduces feeling of hopelessness and thoughts of committing suicide, and restore motivation. Antidepressants medicines take 2 to 4 weeks to start working.

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